心脏感染死亡人数在年轻人中上升

Death rates from a rare heart infection have risen among young adults over the past two decades, a trend that may be driven by complications of substance use disorder, 新的研究表明.

的 研究 showed death rates for infective endocarditis – which develops after bacteria enter the bloodstream and settle in the heart lining, heart valve or blood vessels of the heart – declined in most adults across the U.S. 但在25岁至44岁的人群中有所上升. Findings were published Wednesday in the Journal of the 美国心脏协会.

“我们的研究结果引起了公众对健康的关注, especially since the deaths in younger age groups are on the rise,该研究的主要作者说, Dr. 苏达山·巴拉说 沙巴足球体育平台发布会上. Balla is an associate professor of medicine at the West Virginia University Heart and Vascular Institute at J.W. 摩根敦的鲁比纪念医院. “我们推测这种加速是可能的, 在很大程度上, due to the opioid crisis that has engulfed several states and involved principally younger adults."

以前做过心脏瓣膜手术的人, 阀异常, 人工瓣膜, congenital heart defects or prior infections of the heart are at greater risk for infective endocarditis. But it also can be caused by complications from injecting illicit drugs.

Researchers analyzed death certificate data from the Centers for Disease Control and Prevention to identify state and national death trends related to the condition, 考虑到年龄的差异, 性, 从1999年到2020年的种族和地理. 因为阿片类药物流行病是在这段沙巴足球体育平台内出现的, 他们还研究了与药物使用有关的数据.

感染性心内膜炎的总死亡率, 根据年龄调整, dropped from 26 per million people in 1999 to 22 per million in 2020, 分析表明.

然而, the analysis also showed an average annual increase in deaths of more than 5% for adults 25 to 34 years old and more than 2% for those 35 to 44. 在45到54岁的成年人中, 死亡率停滞不前, 而55岁及以上人群的患病率则大幅下降.

Among adults 25 to 44, substance use disorder was associated with a rise in multiple causes of death. 的 rise in deaths due to infective endocarditis was particularly steep in Kentucky, 田纳西和西弗吉尼亚与其他州相比, 死亡率下降或保持不变的地方.

"We found that substance use was listed as a contributing cause that could explain the higher death rates in the younger age groups and also in the states in those who died due to endocarditis,巴拉说. "Comprehensive care plans for those treated for infective endocarditis should also include screening and treatment for substance use disorder."

A direct cause-and-effect relationship between substance use disorders and increasing deaths caused by infective endocarditis among younger adults could not be determined, 研究人员说, because of the limited medical details available and possible errors in death certificates.

Some states have begun public health programs to reduce the risk of infectious diseases and bacterial and fungal infections caused by intravenous drug use.

But "whether these programs make an impact is yet to be determined,巴拉说.